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Exam prep · USMLE Step 1

USMLE Step 1 flashcards from your own lectures

Step 1 is pass/fail, which changes the goal: broad, reliable recall across every system rather than a chase for a score. Flashcards made from your own lectures and review book are the most direct route there. The decks below cover the shared foundations.

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Updated 2026-10-23. Decks are shared by Quizcard and its users; study them on the page or copy them into a free account.

USMLE Step 1 at a glance

Format
One day of seven 60-minute blocks, up to 40 questions each (maximum 280), all multiple choice with clinical vignettes.
Length
About 8 hours including a 15-minute tutorial and 45 minutes of break time.
Scoring
Pass or fail only (since January 2022). Results typically arrive within a few weeks.
Eligibility
US and Canadian MD/DO students, and IMGs through ECFMG. Register through NBME or ECFMG.

What the USMLE Step 1 tests

  • Systems. Cardiovascular, respiratory, renal, GI, endocrine, reproductive, nervous, musculoskeletal, hematologic, immune, and multisystem processes.
  • Disciplines. Pathology, physiology, pharmacology, biochemistry, microbiology, immunology, anatomy and embryology, behavioral science, biostatistics.
  • Competencies. Medical knowledge, patient care (diagnosis and management), communication, and practice-based learning. Most items are mechanism and diagnosis questions.

Free USMLE Step 1 flashcard decks

  • Nursing Pharmacology: Common Drug Classes30 cards · University · Cardiovascular · Endocrine · Infection · Neuro/psych
  • Anatomy and Physiology: Body Systems Overview30 cards · University · Cardiovascular · Digestive · Endocrine · Immune
  • Medical Terminology: Roots, Prefixes, and Suffixes30 cards · University · Abbreviations · Anatomy terms · Prefixes · Roots
  • Biology: Cell Structure and Function30 cards · High school · Cell basics · Cell cycle · Energy · Organelles
  • USMLE Step 1 Microbiology: High-Yield Bacteria, Viruses and Fungi42 cards · University · Atypical/acid-fast bacteria · Atypical/intracellular organisms · Fungi · GI gram-negative rods
  • ATI TEAS 7 Science: Anatomy and Physiology Review28 cards · University · Anatomical Terminology & Planes · Cardiovascular System · Cell Structure · Gastrointestinal System
  • USMLE Step 1 Pathology: Cell Injury, Inflammation and Neoplasia59 cards · University · Amyloidosis · Apoptosis vs Necrosis · Carcinogens · Cell Injury
  • Nursing Pharmacology: Drug Suffixes, Prefixes and Prototypes33 cards · University · Anesthetics / Pain · Anti-infective · Antiviral / Oncology / Biologic · Cardiovascular
  • Nursing Pharmacology: Antimicrobials and Infection44 cards · University · Aminoglycosides · Antifungals · Antituberculars (RIPE) · Antivirals/Antiretrovirals
  • Nursing Pharmacology: Cardiovascular Drugs35 cards · University · ACE Inhibitors · ARBs · Antiarrhythmics — Adenosine · Antiarrhythmics — Amiodarone
  • Anatomy and Physiology: Muscular and Skeletal Systems40 cards · University · Appendicular Skeleton · Axial Skeleton · Bone Tissue & Cells · Calcium Homeostasis
  • Anatomy and Physiology: Endocrine System and Hormones41 cards · University · Adrenal Glands · Disorders · Feedback Loops · Fundamentals

Missing a topic? Upload the chapter from your prep book and Quizcard builds the deck for you, grouped by topic, with figures kept from PDFs. How it works.

Test yourself: free USMLE Step 1 practice quizzes

  • Nursing Pharmacology: Common Drug Classes quiz18 multiple-choice questions with explanations · no account needed
  • Anatomy and Physiology: Body Systems Overview quiz18 multiple-choice questions with explanations · no account needed
  • Biology: Cell Structure and Function quiz18 multiple-choice questions with explanations · no account needed
  • USMLE Step 1 Microbiology: High-Yield Bacteria, Viruses and Fungi quiz15 multiple-choice questions with explanations · no account needed
  • ATI TEAS 7 Science: Anatomy and Physiology Review quiz15 multiple-choice questions with explanations · no account needed
  • USMLE Step 1 Pathology: Cell Injury, Inflammation and Neoplasia quiz15 multiple-choice questions with explanations · no account needed
  • Nursing Pharmacology: Drug Suffixes, Prefixes and Prototypes quiz15 multiple-choice questions with explanations · no account needed
  • Nursing Pharmacology: Antimicrobials and Infection quiz20 multiple-choice questions with explanations · no account needed
  • Nursing Pharmacology: Cardiovascular Drugs quiz15 multiple-choice questions with explanations · no account needed
  • Anatomy and Physiology: Muscular and Skeletal Systems quiz17 multiple-choice questions with explanations · no account needed
  • Anatomy and Physiology: Endocrine System and Hormones quiz20 multiple-choice questions with explanations · no account needed

Each quiz scores you at the end and explains every answer. Redo it any time; the questions reshuffle.

Sample cards from “Nursing Pharmacology: Common Drug Classes”

Match insulin types to onset and peak.

Answer: Rapid (lispro): onset 15 min, peak 1 h. Regular: onset 30 min, peak 2–3 h. NPH: onset 1–2 h, peak 4–12 h. Long-acting (glargine): no pronounced peak.

Explanation

Hypoglycemia risk is highest at peak times.

What should be monitored with phenytoin?

Answer: Serum levels (10–20 mcg/mL), gingival hyperplasia, and signs of toxicity such as nystagmus and ataxia.

Explanation

Do not stop abruptly; good oral hygiene helps gums.

What range is therapeutic for lithium and what are signs of toxicity?

Answer: About 0.6–1.2 mEq/L; toxicity shows as coarse tremor, vomiting, diarrhea, confusion, and ataxia.

Explanation

Maintain steady sodium and fluid intake; dehydration raises levels.

What dietary restriction applies to MAOIs?

Answer: Avoid tyramine-rich foods (aged cheese, cured meats, red wine) to prevent hypertensive crisis.

Explanation

Includes phenelzine and tranylcypromine.

What is serotonin syndrome and what causes it?

Answer: A dangerous excess of serotonin: agitation, hyperthermia, tremor, diarrhea; caused by combining SSRIs with MAOIs, tramadol, or other serotonergic drugs.

Explanation

SSRIs can take 4–6 weeks for full effect; monitor for suicidal ideation early.

What should patients avoid while taking metronidazole?

Answer: Alcohol, during and for 48–72 hours after, because of a disulfiram-like reaction.

Explanation

Metallic taste is a common side effect.

Showing 6 of 30 cards. Study the whole deck or copy it into your account.

A flashcard study plan for the USMLE Step 1

  1. Pre-dedicated (during courses): upload each lecture PDF the week it is taught and generate a deck into a folder per block. Study the week’s decks every Sunday.
  2. Dedicated weeks 1 to 2: question bank in the morning (80 to 120 questions), cards from your misses in the evening. Keep the card’s front as a one-line vignette.
  3. Dedicated weeks 3 to 4: systems rotation. Each day, one system’s decks plus a mixed question block. Weekly self-assessment.
  4. Dedicated weeks 5 to 6: only the missed deck, pharmacology, and biostatistics equations. Stop new material a week out.
  5. Final two days: a short flip through the missed deck, logistics, rest.

How to write USMLE Step 1 cards that work

  • Write pharmacology cards as mechanism, use, and the one adverse effect the exam loves (for example, “ACE inhibitor: cough, angioedema, hyperkalemia”).
  • For microbiology, card the “buzzword to bug” pairs both ways.
  • Biostatistics: one card per formula with a worked example, including sensitivity, specificity, PPV, NPV, NNT.
  • Keep diagrams. Pathway figures and histology images cropped from your PDFs survive as card images.

Questions

Should I still use Anki for Step 1?

If it works for you, yes. Quizcard is useful for turning this week’s lectures into cards fast; export to CSV and review in Anki if you prefer its scheduler.

Does Quizcard keep the figures from lecture PDFs?

Yes. Figures are cropped from the PDF onto the cards, which matters for pathways, ECGs and histology.

How much does it cost for a full preclinical year?

Making cards by hand is free. Generating from lectures is 10 documents a month on Plus ($6.99) or 40 a month on Pro ($12.99), which also reads longer documents.

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Official information: USMLE: Step 1. Formats and weights change; check the official page before test day.

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